Unpacking a Pandemic

Genetic researchers are making ground-breaking—and possibly life-saving—discoveries about the 1918 flu pandemic.

WASHINGTON (Reuters) — Researchers have found out what made the 1918 flu pandemic so deadly — a group of three genes that lets the virus invade the lungs and cause pneumonia. …

Yoshihiro Kawaoka of the University of Wisconsin and colleagues at the Universities of Kobe and Tokyo in Japan used ferrets, which develop flu in ways very similar to humans. …

“The 1918 influenza pandemic was the most devastating outbreak of infectious disease in human history, accounting for about 50 million deaths worldwide,” Kawaoka’s team wrote. …

“We wanted to know why the 1918 flu caused severe pneumonia,” Kawaoka said in a statement.

They painstakingly substituted single genes from the 1918 virus into modern flu viruses and, one after another, they acted like garden-variety flu, infecting only the upper respiratory tract.

But a complex of three genes helped to make the virus live and reproduce deep in the lungs. The three genes — called PA, PB1, and PB2 — along with a 1918 version of the nucleoprotein or NP gene, made modern seasonal flu kill ferrets in much the same way as the original 1918 flu, Kawaoka’s team found.

Jump to top

Create a PageThis is the LGF Pages posting bookmarklet. To use it, drag this button to your browser's bookmark bar, and title it 'LGF Pages' (or whatever you like). Then browse to a site you want to post, select some text on the page to use for a quote, click the bookmarklet, and the Pages posting window will appear with the title, text, and any embedded video or audio files already filled in, ready to go.
Or... you can just click this button to open the Pages posting window right away.
Last updated: 2016-01-01 10:29 am PST
LGF User's Guide RSS Feeds Tweet

Help support Little Green Footballs!

Subscribe now for ad-free access!Register and sign in to a free LGF account before subscribing, and your ad-free access will be automatically enabled.

Donate with
PayPal
Square Cash Shop at amazon
as an LGF Associate!
Recent PagesClick to refresh
ROXY MUSIC - RE-MAKE/RE-MODEL LIVE at the APOLLO 2001 Cpl593h ROXY MUSIC - RE-MAKE/RE-MODEL LIVE AT THE APOLLO 2001Original by the first Roxy Music Album , the very first song , 1972lyrics below :I tried, but I could not find a wayLooking back, all I did was look awayNext ...
Thanos
1 hour, 25 minutes ago
Views: 49 • Comments: 0 • Rating: 0
Tweets: 1 • Share to Facebook
“Midnight Picnic Near the Ocean” - Forest BaileyRecorded live at Snaggy Mountain in Burnsville North Carolina. 24-bit Studio Master digital download available at: forestbaileymusic.com Buy/Listen:Spotify: open.spotify.comApple Music: music.apple.com Visit Forest BaileyWebsite: forestbaileymusic.comInstagram: instagram.comFacebook: facebook.comYouTube: youtube.comBandsintown: bandsintown.com
Thanos
1 day, 7 hours ago
Views: 200 • Comments: 0 • Rating: 0
Tweets: 1 • Share to Facebook
#Thegreatpoolpondconversion - 191014After three weeks of meh pictures and invisible progress, we were determined to have something to photograph today. And we were eager to start on the upper shelf. We were close, but not quite there, and we were determined! To ...
DangerMan
5 days, 8 hours ago
Views: 368 • Comments: 0 • Rating: 3
Tweets: 0 • Share to Facebook
Jack Klatt - Highway Lines (Live at Radio Heartland)Jack Klatt performs 'Highway Lines' from his 2019 album, 'It Ain't The Same,' live in the studio of Radio Heartland at The Current.
Thanos
1 week ago
Views: 339 • Comments: 0 • Rating: 0
Tweets: 2 • Share to Facebook
Brittany Howard Performing ‘13th Century Metal’ Live on KCRW Brittany Howard's solo debut album Jaime puts her powerhouse vocals on full display. It also takes us front and center to her very personal journey of loss, love and self-discovery. We're thrilled to welcome her back to KCRW to ...
Thanos
1 week, 2 days ago
Views: 534 • Comments: 0 • Rating: 0
Tweets: 1 • Share to Facebook
(15) Rodrigo Y Gabriela - Electric Soul (Live on KEXP) kexp.org presents Rodrigo y Gabriela performing "Electric Soul" live in the KEXP gathering space. Recorded July 14, 2019. Host: Stevie ZoomAudio Engineers: Kessiah Gordon & Kevin SuggsAudio Mixer: David MarchantCameras: Jim Beckmann, Alaia D'Alessandro, Luke Knecht & Justin WIlmoreEditor: ...
Thanos
1 week, 2 days ago
Views: 558 • Comments: 1 • Rating: 1
Tweets: 2 • Share to Facebook
Fresh Air (Remastered) Quicksilver Messenger Service Provided to YouTube by Universal Music Group Fresh Air (Remastered) · Quicksilver Messenger Service Classic Masters ℗ 2001 Capitol Records, LLC Released on: 2007-01-01 Producer: Quicksilver Messenger ServiceStudio Personnel, Mastering Engineer: Robert VosgienComposer: Jesse Oris Farrow Auto-generated by YouTube. ...
Thanos
1 week, 2 days ago
Views: 613 • Comments: 0 • Rating: 2
Tweets: 2 • Share to Facebook
Jon Anderson - Song of SevenFrom the 1980 album "Song of Seven".
Thanos
1 week, 4 days ago
Views: 636 • Comments: 0 • Rating: 0
Tweets: 1 • Share to Facebook
#Thegreatpoolpondconversion - 191006 Today we have to take a few steps back in explanation. The pond is going to have three levels. Sort of an upside down ziggurat. The lowest level, in the center we call ‘the channel’. After the liner is ...
DangerMan
1 week, 6 days ago
Views: 756 • Comments: 0 • Rating: 4
Tweets: 0 • Share to Facebook
Jon Anderson - Change We MustFrom the 1994 album "Change We Must".
Thanos
2 weeks, 1 day ago
Views: 820 • Comments: 0 • Rating: 0
Tweets: 2 • Share to Facebook