Pages

Jump to bottom

5 comments

1 researchok  Mon, Dec 19, 2011 1:06:12pm

I wonder how many shares of Pfizer were sold during that 2 day period between the PR blitz and the announcement the torcetrapib trials were being discontinued.

They probably made money going long and then again shorting the stock.

2 Locker  Mon, Dec 19, 2011 1:08:41pm

This isn’t science which is failing us.. it’s drug company marketing that’s failing.

3 Political Atheist  Mon, Dec 19, 2011 2:01:25pm

re: #2 Locker

This isn’t science which is failing us.. it’s drug company marketing that’s failing.

Try reading the article through. It’s not about zealous marketing.

4 Locker  Mon, Dec 19, 2011 2:35:00pm

It’s not about science failing either it’s about scientists failing by not using the right model. Why? Because the right model takes a whole lot longer. So why not use the longer method? Money. Marketing. Get approved, push the stock up.

5 Political Atheist  Mon, Dec 19, 2011 2:47:56pm

re: #4 Locker

It’s not about science failing either it’s about scientists failing by not using the right model. Why? Because the right model takes a whole lot longer. So why not use the longer method? Money. Marketing. Get approved, push the stock up.

Not really-

But here’s the bad news: The reliance on correlations has entered an age of diminishing returns. At least two major factors contribute to this trend. First, all of the easy causes have been found, which means that scientists are now forced to search for ever-subtler correlations, mining that mountain of facts for the tiniest of associations. Is that a new cause? Or just a statistical mistake? The line is getting finer; science is getting harder. Second—and this is the biggy—searching for correlations is a terrible way of dealing with the primary subject of much modern research: those complex networks at the center of life. While correlations help us track the relationship between independent measurements, such as the link between smoking and cancer, they are much less effective at making sense of systems in which the variables cannot be isolated. Such situations require that we understand every interaction before we can reliably understand any of them. Given the byzantine nature of biology, this can often be a daunting hurdle, requiring that researchers map not only the complete cholesterol pathway but also the ways in which it is plugged into other pathways. (The neglect of these secondary and even tertiary interactions begins to explain the failure of torcetrapib, which had unintended effects on blood pressure. It also helps explain the success of Lipitor, which seems to have a secondary effect of reducing inflammation.) Unfortunately, we often shrug off this dizzying intricacy, searching instead for the simplest of correlations. It’s the cognitive equivalent of bringing a knife to a gunfight.


This page has been archived.
Comments are closed.

Jump to top

Create a PageThis is the LGF Pages posting bookmarklet. To use it, drag this button to your browser's bookmark bar, and title it 'LGF Pages' (or whatever you like). Then browse to a site you want to post, select some text on the page to use for a quote, click the bookmarklet, and the Pages posting window will appear with the title, text, and any embedded video or audio files already filled in, ready to go.
Or... you can just click this button to open the Pages posting window right away.
Last updated: 2021-06-05 2:51 pm PDT
LGF User's Guide RSS Feeds Tweet

Help support Little Green Footballs!

Subscribe now for ad-free access!Register and sign in to a free LGF account before subscribing, and your ad-free access will be automatically enabled.

Donate with
PayPal
Cash.app Shop at amazon
as an LGF Associate!
Recent PagesClick to refresh
Knees of Fire — the ChairProvided to YouTube by IDOL Knees of Fire · The Chair The Road to Hammer Junkie ℗ The Chair Released on: 2013-02-01 Auto-generated by YouTube.
Thanos
6 days, 14 hours ago
Views: 437 • Comments: 0 • Rating: 0
Tweets: 3 •
Jack White - Taking Me Back (Gently) [Visualizer] Visualizer for Jack White’s new song “Taking Me Back (Gently)” Listen to “Taking Me Back” & “Taking Me Back (Gently)”: ffm.to Directed by Ben Chappell Additional art + editing: Jordan Williams, Brad Holland, Quinton Hickman, Rob Jones Follow Jack ...
Thanos
6 days, 15 hours ago
Views: 448 • Comments: 0 • Rating: 0
Tweets: 2 •
Cross Bones Style — Jason Isbell, Amanda Shires Provided to YouTube by The Orchard Enterprises Cross Bones Style · Jason Isbell and the 400 Unit · Amanda Shires · Charlyn Marie Marshall Georgia Blue ℗ 2021 Southeastern Records marketed and distributed by Thirty Tigers Released on: 2021-10-15 ...
Thanos
1 week ago
Views: 497 • Comments: 0 • Rating: 0
Tweets: 4 •
Jon Batiste - SING Ft. Tori Kelly Order my album ‘WE ARE: The Deluxe Edition’: jon-batiste.lnk.to Shop merch: jonbatistestore.com Director : Content Video Follow Jon:Instagram: jon-batiste.lnk.to Facebook: jon-batiste.lnk.to Twitter: jon-batiste.lnk.to Spotify: jon-batiste.lnk.to Apple Music: jon-batiste.lnk.to Amazon: jon-batiste.lnk.to Soundcloud: jon-batiste.lnk.to Pandora: jon-batiste.lnk.to YouTube Music: jon-batiste.lnk.to Official Website: ...
Thanos
1 week, 1 day ago
Views: 586 • Comments: 0 • Rating: 0
Tweets: 0 •
An Exercise in Rock & Roll Improvisation - Umphrey’s McGee: UMBowl 2021 Stew Art 10/09/21 UM kicked off night two of UMBowl 2021 with only the 7th “Stew Art” set ever, where fans texted in concepts and the band created new improvised music on the spot based off of the ideas presented on the ...
teleskiguy
1 week, 3 days ago
Views: 653 • Comments: 0 • Rating: 1
Tweets: 3 •
BADBADNOTGOOD - Love Proceeding Taken from the album, Talk Memory. Out October 8th on XL Recordings and Innovative Leisure. Out now: badbadnotgood.ffm.to Many thanks to all our friends and the fabulous people who came together for this film. Written and Directed by Jamal ...
Thanos
2 weeks ago
Views: 781 • Comments: 0 • Rating: 0
Tweets: 3 •