Twinkies at Wikipedia, or more than you ever wanted to know

This includes a lengthy section on cultural references, including this anecdote:

In the 2012 Ghost Rider: Spirit of Vengeance, the character Blackout has the power to decay anything he touches. When going through a lunch he causes a sandwich and apple to decay in seconds, then is impressed when he is unable to cause a Twinkie inside the lunch to decay.

(As the article points out, the Twinkies’ infinite shelf life is an urban legend. The actual shelf life is still an impressive 25-30 days.)