Can anyone guesstimate how long it will take for speciation to be demonstrated in the laboratory? A decade or few? By the end of the century? (Could it happen via simulation on a megasuperdupercomputer before it happens in the lab?)

Barring a civilizational extinction event, such experiments will be done. Hopefully they will be done prudently under secure conditions. If they’re not done in North America or Europe, they’ll be done elsewhere, most likely in Asia. They will be opposed by devotees of Gaia and Jesus.