Unless we can figure out a way to go 99.9% of the speed of light, so that the trip only takes the travelers 3% of the elapsed time of those of us stuck back here on Earth.

But then the mass of the spaceship will require an AWFUL LOT of motive power to get going that fast!

The other options are 1) find a way to get around the Theory of Relativity - a favorite of science fiction writers, or 2) send out huge space “seedships” where generations can live on their way to a star that might or might not have a habitable planet.