16 January 2003, 15:40:21.7 UTC, T plus 00:0 1:21.7

16 January 2003, 15:39:00 UTC, T minus Zero: Space Shuttle Columbia (STS-107) lifted off from Launch Complex 39A at the Kennedy Space Center, Cape Canaveral, Florida.

Columbia (OV-102) was America’s first space shuttle. This would be her final flight.