Daredevil Volume 1, Issue 16: “Enter…Spider-Man!”
Daredevil #16, published in May 1966, featured one of those “mistaken identity” battles between Daredevil and yes, Spider-Man. The Masked Marauder tricked Spider-Man into thinking Daredevil was his enemy; Marvel superheroes were always falling for this one.
And what’s more, DD kicked Spidey’s ass. I don’t need to tell you how difficult that was.
(The Lizard Collection copy of this classic comic is in excellent condition, with super-bright inks, white pages, and just a few creases on the cover.)